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Center director:
Prof. Niels Tommerup
tommerup@imbg.ku.dk







Centre contact information

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Kasper Lage Hansen

Master student / Stud.scient.humanbiologi

Computationally Disease Gene Finding

EmailLage.Kasper@mgh.harvard.edu

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Publications related to WJC

6.   Lage K, Greenway SC, Rosenfeld JA, Wakimoto H, Gorham JM, Segrè AV, Roberts AE, Smoot LB, Pu WT, Pereira AC, Mesquita SM, Tommerup N, Brunak S, Ballif BC, Shaffer LG, Donahoe PK, Daly MJ, Seidman JG, Seidman CE, Larsen LA. Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development. Proc Natl Acad Sci U S A. 2012;109:14035-40.
 
5.   Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham JM, Workman CT, Bendsen E, Hansen NT, Rigina O, Roque FS, Wiese C, Christoffels VM, Roberts AE, Smoot LB, Pu WT, Donahoe PK, Tommerup N, Brunak S, Seidman CE, Seidman JG, Larsen LA. Dissecting spatio-temporal protein networks driving human heart development and related disorders. Mol Syst Biol. 2010 Jun 22;6:381.
 
4.   Brudzewsky D, Pedersen AE, Claesson MH, Gad M, Kristensen NN, Lage K, Jensen T, Tommerup N, Larsen LA, Knudsen S, Tümer Z. Genome-wide gene expression profiling of SCID mice with T-cell-mediated Colitis. Scand J Immunol. 2009;69:437-46.
 
3.   Jakobsen LP, Borup R, Vestergaard J, Larsen LA, Lage K, Maroun LL, Kjaer I, Niemann CU, Andersen M, Knudsen MA, Møllgård K, Tommerup N. Expression analyses of human cleft palate tissue suggest a role for osteopontin and immune related factors in palatal development. Exp Mol Med. 2009;41:77-85.
 
2.   Sanggaard KM, Rendtorff ND, Kjaer KW, Eiberg H, Johnsen T, Gimsing S, Dyrmose J, Nielsen KO, Lage K, Tranebjaerg L. Branchio-oto-renal syndrome: detection of EYA1 and SIX1 mutations in five out of six Danish families by combining linkage, MLPA and sequencing analyses. Eur J Hum Genet. 2007;15:1121-31.
 
1.   Lage K, Karlberg EO, Størling ZM, Ólason PI, Pedersen AG, Rigina O, Tumer Z, Pociot F, Tommerup N, Moreau Y, Brunak S. A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol. 2007;25:309-16.
 

Presentations related to WJC

58th Annual Meeting of The American Society of Human Genetics
Philadelphia, Pennsylvania, November 11, 2008
Posters
1.   Larsen LA, Lage K, Møllgård K, Workman CT, Bendsen E, Tommerup N, Brunak S. Systematic Identification of Functional Networks in Human Heart Development.
 

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