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Center director:
Prof. Niels Tommerup
tommerup@imbg.ku.dk







Centre contact information

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Claus Hansen

Claus Hansen

Research Associate Professor / Forskningslektor

Molecular biology and genetics, bioinformatics. Gene cloning and characterization. Real time PCR. Mutation screening. Automation by robotics. Supervision of master- and Ph.d.-students

Emailcph@imbg.ku.dk
Phone27846

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Publications related to WJC

16.   Halgren C, Kjaergaard S, Bak M, Hansen C, El-Schich Z, Anderson CM, Henriksen KF, Hjalgrim H, Kirchhoff M, Bijlsma EK, Nielsen M, den Hollander NS, Ruivenkamp CA, Isidor B, Le Caignec C, Zannolli R, Mucciolo M, Renieri A, Mari F, Anderlid BM, Andrieux J, Dieux A, Tommerup N, Bache I. Corpus Callosum Abnormalities, Mental Retardation, Speech Impairment, and Autism in Patients with Haploinsufficiency of ARID1B. Clin Genet. 2012 Sep;82(3):248-55.
 
15.   Minocherhomji S, Seeman S, Mang Y, El-schich Z, Bak M, Hansen C, Papadopolous N, Nielsen H, Josefsen K, Gorodkin J, Tommerup N, Silahtaroglu A. Sequence and expression analysis of gaps in human chromosome 20. Nucleic Acids Res. 2012 Apr 17. [Epub ahead of print].
 
14.   Kragelund C, Hansen C, Reibel J, Nauntofte B, Broesen K, Pedersen AM, Smidt D, Eiberg H, Torpet LA. Polymorphic drug metabolizing CYP-enzymes--a pathogenic factor in oral lichen planus?. J Oral Pathol Med. 2009;38:63-71.
 
13.   Kragelund C, Hansen C, Torpet LA, Nauntofte B, Brøsen K, Pedersen AM, Buchwald C, Therkildsen MH, Reibel J. Expression of two drug-metabolizing cytochrome P450-enzymes in human salivary glands. Oral Dis. 2008;14:533-40.
 
12.   Torarinsson E, Yao Z, Wiklund ED, Bramsen JB, Hansen C, Kjems J, Tommerup N, Ruzzo WL, Gorodkin J. Comparative genomics beyond sequence-based alignments: RNA structures in the ENCODE regions. Genome Res. 2008;18:242-51.
 
11.   Moller R, Hansen C, Jackson G, Ullmann R, Ropers H, Tommerup N, Tumer Z. Interstitial deletion of chromosome 4p associated with mild mental retardation, epilepsy and polymicrogyria of the left temporal lobe. Clin Genet. 2007;72:593-8.
 
10.   Bugge M, Collins A, Hertz JM, Eiberg H, Lundsteen C, Brandt CA, Bak M, Hansen C, Delozier CD, Lespinasse J, Tranebjaerg L, Hahnemann JM, Rasmussen K, Bruun-Petersen G, Duprez L, Tommerup N, Petersen MB. Non-disjunction of chromosome 13. Hum Mol Genet. 2007;16:2004-10.
 
9.   Jakobsen LP, Ullmann R, Christensen SB, Jensen KE, Mølsted K, Henriksen KF, Hansen C, Knudsen MA, Larsen LA, Tommerup N, Tumer Z. Pierre Robin sequence may be caused by dysregulation of SOX9 and KCNJ2. J Med Genet. 2007;44:381-6.
 
8.   Jorgensen JR, Juliusson B, Henriksen KF, Hansen C, Knudsen S, Petersen TN, Blom N, Seiger A, Wahlberg LU. Identification of novel genes regulated in the developing human ventral mesencephalon. Exp Neurol. 2006;198:427-37.
 
7.   Eiberg H, Hansen L, Hansen C, Mohr J, Teglbjaerg PS, Kjaer KW. Mapping of hereditary trichilemmal cyst (TRICY1) to chromosome 3p24-p21.2 and exclusion of beta-CATENIN and MLH1. Am J Med Genet A. 2005;133:44-7.
 
6.   Bak M, Hansen C, Henriksen KF, Hansen L, Pakkenberg H, Eiberg H, Tommerup N. Mutation analysis of the Sonic hedgehog promoter and putative enhancer elements in Parkinsons disease patients. Brain Res Mol Brain Res. 2004;126:207-11.
 
5.   Bak M, Hansen C, Tommerup N, Larsen LA. The Hedgehog signaling pathway-implications for drug targets in cancer and neurodegenerative disorders. Pharmacogenomics. 2003;4:411-29 (Review).
 
4.   Harboe TL, Jensen LR, Hansen C, Horn P, Bendixen C, Tommerup N, Tumer Z. Cloning, characterization and chromosomal localization of the Sus scrofa SLC31A1 gene. Anim Genet. 2003;34:59-61.
 
3.   Kjaer KW, Hedeboe J, Bugge M, Hansen C, Friis-Henriksen K, Vestergaard MB, Tommerup N, Opitz JM. HOXD 13 polyalanine tract expansion in classical synpolydactyly Type Vordingborg. Am J Med Genet. 2002;110:116-21.
 
2.   Tumer Z, Croucher PJ, Jensen LR, Hampe J, Hansen C, Kalscheuer V, Ropers HH, Tommerup N, Schreiber S. Genomic structure, chromosome mapping and expression analysis of the human AVIL gene, and its exclusion as a candidate for locus for inflammatory bowel disease at 12q13-14 (IBD2). Gene. 2002;288:179-85.
 
1.   Harboe TL, Tumer Z, Hansen C, Jensen NA, Tommerup N. Assignment of the human zinc finger gene, ZNF288, to chromosome 3 band q13.2 by radiation hybrid mapping and fluorescence in situ hybridisation. Cytogenet Cell Genet. 2000;89:156-7.
 

Presentations related to WJC

European Human Genetics Conference 2002
Strasbourg, France, May 24, 2002
Oral presentations
1.   Kjaer KW, Hedeboe J, Bugge M, Hansen C, Friis-Henriksen K, Opitz JM, Tommerup N. A systematic study of limb defects in Denmark. Eur J Hum Genet 2002:10(supp);67 (C31).
 

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